CRESTOR is a registered trademark of the AstraZeneca group of companies. ©2009 AstraZeneca Pharmaceuticals LP. Al rights reserved. 269884 5/09

30 YEARS AGO,

YOU DIDN'T KNOW ABOUT

HIGH CHOLESTEROL

AND PLAQUE BUILDUP.

FORTUNATELY, NOW YOU DO.

Over time, you've learned a thing or two. Now you know that high

cholesterol is a major factor in the buildup of plaque in arteries.

Here's how CRESTOR can help.

Along with diet, CRESTOR does more than V ' lower bad cholesterol. It

raises the good

CRESTOR is also proven to slow the buildup of plaque in arteries as part of a treatment plan

to lower cholesterol to goal

TAKE A DEEPER LOOK

High cholesterol, family history of early heart disease, diabetes, and high blood pressure

may play a role in plaque buildup

Talk to your doctor about plaque buildup, and ask if CRESTOR is right for you.

Important Safety Information about CRESTOR: In adults, CRESTOR is prescribed along

with diet for lowering high cholesterol. CRESTOR is also prescribed along with diet to slow

the progression of atherosclerosis (the buildup of plaque in arteries) as part of a treatment

plan to lower cholesterol to goal. CRESTOR has not been approved to prevent heart disease,

heart attacks, or strokes.

at how plaque could be

building in your arteries.

Take an interactive

tour of an artery at

CRESTOR.COM

CRESTOR is not right for everyone, including anyone who has previously had an allergic

reaction to CRESTOR, anyone with liver problems, or women who are nursing, pregnant,

or who may become pregnant. Your doctor will do blood tests before and during treatment

with CRESTOR to monitor your liver function. Unexplained muscle pain and weakness could

be a sign of a rare but serious side effect and should be reported to your doctor right away.

The 40-mg dose of CRESTOR is only for patients who do not reach goal on 20 mg. Be sure

to tell your doctor if you are taking any medications. Side effects occur infrequently and

include headache, muscle aches, abdominal pain, weakness, and nausea.

Please read the important Product Information about CRESTOR on the adjacent page.

If you’re without prescription coverage and can’t afford your medication, AstraZeneca

may be able to help.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.FDA.gov/medwatch, or call 1-800-FDA-1088.

CRESTOR

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CRESTOR.COM

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